The forest is well known to habour a number of primates like the olive baboons, black and white monkeys, grey monkeys black and white colobus and many others plus the famous chimpanzees. Elephants can also be spoted in this forest park espcially the forest elephants. The vast Forest lies at the edge of the Albertine Rift Valley and to the South of Murchison falls National Park. The Forest habours a number of sought-after birds such as the Nahan's Francolin, Cassin's Spinetail, Ituri Batis, Puvel's Illadopsis and Chestnut-capped Flycatcher.
The Royal Mile and Busingiro Areas are considered by some birders to be the Country's Premier Forest Birding Locality and among the many birds to see are the Chocolate-backed, Blue-breasted and African Dwarf Kingfishers, White-thighed and Piping Hornbills, Yellow-spotted, Hairy-Breasted and Yellow-billed Barbets, Red-sided Broadbill, Green-breasted Pitta, Spotted Greenbul. In fact Budongo Forest is the only site in Uganda for the localized Yellow-footed Flycatcher, which favours the understorey of open, Ironwood-dominant forest.
The area just before Sonso River is an excellent place to scan for Black Sparrow hawk, the rare Black-collared Lovebird, Shining Blue Kingfisher.